Immediate vs delayed venous thromboembolism prophylaxis following spine surgery: Increased rate of unplanned reoperation for postoperative hematoma with immediate prophylaxis
i) Study Design: Single institution retrospective cohort study
ii) Of 8,704 patients, a total of 98 (1.13%) VTE events occurred, of which 43 (0.49%) were pulmonary embolism. Fifty-four patients (0.62%) had unplanned reoperations for postoperative hematomas.
iii) Delayed chemoprophylaxis protocol may mitigate postoperative hematoma formation without increasing the risk for a thrombotic event.